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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa53f13f9e288d0c918f73f7e34b1d72dddb914d9bdbb7127546e60f6ac9a1b' 
  AND token = 'I91qAwLJUV2Tny3jJ0Ezc9GkbPAUhZRGxZoAYF1uS2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}