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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66cfa246e348f7b484594ef7e4e1614dff9dab2d77482b69ddc18756b8e08141' 
  AND token = '4E3o7jWejruzMxoXYvpLxTa+TyiBQWTnruD8BpygQ9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}