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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c498e041d76371eb8c7d99ea4ceb46b4405ff8d55d91fae997d7a99a3244f2a2' 
  AND token = 'EhzsUWHT1qcU5YPXkzyKiCSD+ena7HtT5TPVQ4IPHRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}