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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87876e521ab41df68970f63bfc9ee6010393718cfc7e9e837425787c64b854dd' 
  AND token = 'AX0IzxMfFm+Y+nUSOVPbZ1D7PUajZPXjTu6lj8D7GU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}