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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46684046bc0b5ca9cff0c5f6333ddf6d4eb055c706b339dfe575ef140ed3ea14' 
  AND token = 'HQVQtBhyUyR9ENRiZ1eqKx5Yi6ja/w5CKdnQLTB/1ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}