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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406f8f4613ee374ed76e1fa66841ed5fb7537ebc83fd41fb7dc40c7177dd04ec' 
  AND token = 'Z1F7f+2wOGoaJB0rtgF2ZdhC0546TztcFtVkO5B4RGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}