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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17526c2d4fd87bcfee65404e0607abb7957b39db9c2b30b2b21323208dec4940' 
  AND token = 'X40UAzdy4hyVW9pYyDs0TKStiJTp1lMDBJkn6IvgO4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}