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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99be89802f7c3b0b0110276699bd8a16d56c28b587fc4d3401a30fee7b4aa164' 
  AND token = 'oNG6qkstsEYCFbT3MhVunbGIVAnNRqZV7ITZGD4wjmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}