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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afacbc2a52dc5fd851ea7e93a36b828d40aae9d0475dfe7cc0cdbd7826401c63' 
  AND token = 'u35iTeShjZ3A+lbhZrFXA6cWld0EoNi0HzCOik8Qzp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}