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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'beff8394f0f0f5c3233775813a1d37948508b3781370e0775f4ac5aa74cca251' 
  AND token = '3b/uWxQ7fPcnsartu1Qq6TUnoKwvFAzu+D5o5Y20WTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}