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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25334f19e35fe6e49c0b2d46b6d3687d244a7cb332332551b036dbe8b8c74f50' 
  AND token = 'zH59b+Y1qK0pPdJL16W1PYfQ8eqVDdXauMeBGeRWtW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}