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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67cbb7523d5c8354a9990070b0fd0660f11dd303f8121881015e2f7314a57213' 
  AND token = 'onDK+ts3GuRepvOtbgY+dbSWCJn96B2cfIshRtbjRQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}