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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '018718e453b8946fb8fa1fc03b1619dc7ae263f1e737e2094dc68608eb060950' 
  AND token = 'XYG7Hz3ZHzQLpKQ4iYWUO6ITaujjbnadUQAYwrZJnQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}