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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5336c8106d8ebc90d3578be071386b4b6e132e3bbaf1850604e8ab6421ef4ab7' 
  AND token = 'jP8ghP2pD3VezGNf1MG5LdCeplt3cbmwAQqzkQdiT0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}