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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48ce37683125256d8dde3b38b5787b2275388ab8cb53edb47d6405789747946a' 
  AND token = 'YJt86W9Op91cvc7vqzZQNnqoqiLwvHE6pXh9CSi64js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}