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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb0a8ad8bae66fa4885adedbcb2174e855fab7b890480156ccd5ed4db3007f5' 
  AND token = 'TQAQhqQVfUE1A3kN4Wi7l5VJS7JlDevdAyq5ijYYWxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}