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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39f30e427540f90ff0cc943515d2bfebfcee94fa292d7d0a5e6b60f22e5276a6' 
  AND token = 'IAEVE5DCzsMVci82Sjx/X0si3LU1/hsfrU6grpKpjrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}