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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c603757b2adcc9f225412f05760dcf15aa78347533973418893cc4130750727' 
  AND token = 'PE9ov45RYOytDF0pqDGRkQ6GHtqHtwes/YP1YthBAj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}