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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cccba5d177888c89e70d5d44a7dd567a95b2c571e31daa1f3ddb779ae6b83ec5' 
  AND token = 'w7XR1Q++iH/VDTJmSNOsQhQJ2pqzacX5oC9o2MFF1vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}