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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b499309fc0100fe01b87f290a02b347448d86ebc37c84e7ba97028bcf4bbc5' 
  AND token = 'YAr1X1iU2Zu54XN96bXK+qE4qQG5lLs5AXXiR/+RrEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}