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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a7065af5c98c2166f145612a72b61c27edb18ce799840e520ffb076a157e3f' 
  AND token = 'MTmAoQZu2X9tfb37A6ziaKyYlqqzIlsKO4oRdSDw0G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}