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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88cf8efdcafbaf7fe1c82c4d055daa4b0daa52b2740880b9b9e4805423522c77' 
  AND token = 'B3e93P1Q/h+1zuBSVXNSimTHwc/d0JPS0UWgXGLmM1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}