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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c72003313f7fe1a98d1ae51ce1a0da12dbb8afddad6483a60ce318087ea6d7' 
  AND token = 'Ikya08qj4Y1SF/wlA5GUNFIrDcWMuuCgvOj5OY4WXPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}