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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9049cfc83b70ed4ec36a3878a54fa806e8b8d6db2600c82ff42a27b209ab8cf4' 
  AND token = 'jqOT12i+khcvP6eHeqcG51asSnaip5eVOifBHKGEtDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}