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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb622df7f73b243b2d90b346ebb343c3e4a7208a245ed9cbdea77ecd49ed56b4' 
  AND token = 'ZpEVqCnY3sRWz07yV4JP3pKeRqSt6STapBPhQsBZMfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}