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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16b76216e4bf61e80ed059ba75eedb51ce80f52a5144d03a6060ae11c4315067' 
  AND token = 'FwGwNZH1eaWADCpsuMjT7x8DsUg0sa6C56YEPpIZ9IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}