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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae6f0179a06055e6419b125ac35438280ecdb1ebf8b4a593d081bf6b6bdcb08' 
  AND token = 'RelpOU1SFPQE919h+URirzX5EK9dNguV3cL7Gw5XWDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}