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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '251494b357107015dc6315917c908453d8687fe10379cb6b55f7d94b42600c25' 
  AND token = 'IKWOp9070XTDlfC5KEoqvsyW3M15Mfwe9Mc2u0XIld8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}