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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '260ecdf1556692e280a80cd6d49f006c13c866cd44e8f9a66857d858b29085a3' 
  AND token = 'KeQTcdzvsNUp1l3GJmi3cSu+MSjzVC/P1c6EYpGY25k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}