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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ba13b77bdb3974e4d9187f1786daf4e0eb0fb8e21839016d41e6322dbc5946c' 
  AND token = 'PdXpKW0Ol2zzBK6kSXabnJj+WRcupY1SI8LO8hR4fyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}