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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e846299945472369de30d0dcc76d7c2b88f661b3e446e9e49f34c6d5b760f6c' 
  AND token = 'wCCQlbSFrvpqZV6ZdS54if1jn0xtvnqGuH9yvFVknVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}