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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ecc455d0bf8a87feacb0619d36b8acd9adec9998d8715498b3e2c243ac7e229' 
  AND token = 'EVCtluu7N7CGyoRhBokIw8jAKItppfAFRiC2jVQ5EyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}