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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09f20481e0cdbd7b1e9a426a1088aeda4dce9bdf58e3576cc10da103685c738b' 
  AND token = 'HGnQaCtyMZCyOMvBj17PysyhAg56UUMCVHRw4aU/4Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}