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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e59bcce40f4a60aa1256fcfb6a00fd38ee045b01f2b0cb36ffc7dd617081bb7c' 
  AND token = 'UH0686N7WxoNFYhg9RSn0sKM+8+ZYWjk+qQdzvF3Z6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}