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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f33397d40043e0f4334f3cee3ab0a05b4ab3a19cce0298536b1be7fb8331c438' 
  AND token = 'fDnfir1VnwwNu5mfVBR0pW6kEAOsz07i59XytmXkHk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}