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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21570a87313a0c42aa697c6b8a5175ff7a5d8919e13a5350ece7e1fa21ffd221' 
  AND token = 'ok/Mli01JL4JPNXvnznBBA2ix4R2t2njOoLC4hXOt3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}