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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bfe796fb1f266a3a773537cc912907cf39ccb065c0b20702b167008e6b93ca0' 
  AND token = 'VwO3Hs/EYddbZZE2eEyI4Y7qzbyDjU0lWpaFVy6PgRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}