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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c7e87238fc546a06f2aaf7f59156516b18ef264eab81bbf3b2de1a4214f1661' 
  AND token = '4GDBvOoma7OaQgftmEOa/XTpEb+9tqwh6h8RGCiz7Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}