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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c46411081444ea7d8e1603dde631a430680a564da8bfc037e65b1fabe3d7115' 
  AND token = 'K5OLvTUq8ESOUrEU4Pl2kyBXt6IsoC3ZLFumTUKBd9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}