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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5038ed824f433e96491720fe68826d333d8b9401bef330fbb5232ed152a3b62' 
  AND token = 'Gb8frzCzrY6zAws+8IxbNhbqzPcp+uymTgG9LvDeltk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}