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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3976de2167a719f39d1fadd78f48438de55aea0fae6f28396e64987b99a87652' 
  AND token = 'uSNGURaVPwJAQ3pGbjSH/nI7A7atTBXqTHWQAkqGgto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}