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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce0a1ad667a3a38298b70956678d95b666375d75c8d04f30b6721ebad0fd16ad' 
  AND token = 'ag2QG1nxbPDVkmVE3aXI9ozxxuevaQLVEGP9wl9eDSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}