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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c2bd4a2853929d30bef5d013f2d7fd74ce4d01519177315155b728f43d324ae' 
  AND token = 'pKlKUi2jxl19BMm+7QowbnzTXwUa+piYWpO+eV0Ra6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}