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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48a5217d9c1dd70a7e40812204da971d855fa2a2749135b0cde53547d4905c4e' 
  AND token = '+IE/EELSiIn7CjdXy48XX9ID0fE75YiXrD+ZXahb0pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}