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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '282f70ff9e8128e9fc21fc546e1c5205e2f73db7727771d9e05e78fe70c3ded2' 
  AND token = 'kf4DGI0/ZvcPy3S2IGFeLroXNPcdpU/nMW8bovVo9ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}