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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e95fffe22fa8caa46a03f6f8c661ad43993035f6f5ed493b8d34ddda20f18d2' 
  AND token = 'TgCc98wC/eXXCHSj19QLx4iYvxwQUiuzJqS4HQK1Dpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}