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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5365d28e06b2921da192bc750ae66e2fb69b8ea2d0c6f08066b60fce9f6e26b8' 
  AND token = 'kOMyaXVM+09YG1sI5Mu9DJU6B/1LFH6hxBA660N1ORg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}