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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100d1dcaabd6727f22aef5be4e301f2ad9499364bfb70685291155d00e0095aa' 
  AND token = 'PvTnhhxP0CyHxhI5rfLeAzP2hZL9beULYh2RTIr4/dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}