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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9cb744980500d4711240424bac28bd397e902d10d563debfc9e788a1dc007e9' 
  AND token = '42kyN7xWKIshQoCDbui+/xJKAwkKkFfWUhRMaywJa1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}