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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4095eed55ed89d0586df4e921265ce9da2e04d8dbb7a38b002f40783995a57e3' 
  AND token = 'ld8gQTH4yWEPYSwbxzzz2gMvA+ZvRVfBUSzNsg2r4ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}